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KMID : 0359319610010010065
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Korean Journal of Veterinary Research
1961 Volume.1 No. 1 p.65 ~ p.70
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PATHOLOGIC STUDIES ON SODIUM MONOFLUOROACETATE ( COMPOUND 1080 ) POISONING IN RABBITS
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Abstract
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Many losses in domestic animals have been reported in this country, since sodium monofluoroacetate (Compound 1080) was used as a rodenticide.
Lesions described inclubed multiple petechiae in epi- and endocardium, lung and intestinal mucosa, or superficial necrosis of the gastric mucosa.
In this studies as to the poisoning 7 rabbits were administered 0.6㎎ (Group Ⅰ). 0.4㎎ (GroupⅡ), and 0.3㎎ (GroupⅢ) of sodium monofluoroacetate per kilogram of body weight, and the results obtained were as follows:
In addition to the changes mentioned above fatty degeneration in central parts of hepatic lobule or nut meg liver, haemorrhagic feci in cerebral cortex and leptemeninges and fatty degeneration in kidney and cardiac muscles were found.
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KEYWORD
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